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TOP STITCHES

  • New Antibiotic Standard May Transform Pancreatoduodenectomy Outcomes
    Broad-spectrum penicillin-based antibiotics significantly improve outcomes after pancreatoduodenectomy compared to standard care options. Surgical site infections dropped by 47% (OR 0.53), and postoperative pancreatic fistula rates decreased by 38% (OR 0.62). Patients had shorter hospital stays, averaging 2 days less (MD -2.02). Implementing broad-spectrum antibiotics could redefine surgical management and reduce complication rates, especially for patients with preoperative biliary drainage. In that subgroup, surgical site infections decreased by 55% (OR 0.45) and mortality by 66% (OR 0.34). Meta-Analysis by Harnoss… Read more: New Antibiotic Standard May Transform Pancreatoduodenectomy Outcomes

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