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TOP STITCHES

  • Prophylactic Insulin Improves Glycemia in Major Surgery
    In nondiabetic patients undergoing major abdominopelvic surgery, prophylactic glucose-insulin-potassium infusion was feasible and improved perioperative glucose control without severe hypoglycemia. In this pilot trial, 103 patients were randomized; 97% completed treatment, with no severe hypoglycemic episodes. Euglycemia occurred in 42% with prophylactic insulin versus 27% with placebo. Hyperglycemia occurred in 37% versus 48%, and treatment insulin was needed in 26% versus 45%. Complications were less frequent with prophylaxis (12% vs. 21%), but confidence intervals were wide and the study was… Read more: Prophylactic Insulin Improves Glycemia in Major Surgery

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