Analyzing 634 nonmetastatic pT4a colorectal cancer patients (2015–2021), researchers compared minimally invasive surgery (MIS) and laparotomy outcomes. MIS exhibited lower blood loss, quicker recovery parameters, and a 3.5% conversion rate. After 5 years, MIS showed comparable overall survival (72.7%) and disease-free survival (72.2%) to laparotomy. Multivariate analysis identified age, lymph node metastasis, and carcinoembryonic antigen levels as independent variables for overall survival, while lymph node metastasis and CA125 levels were relevant for disease-free survival. MIS proves safe, accelerates recovery, and doesn’t compromise oncological outcomes.
Journal Article by Guo HL, Chen JY (…) Wu WH et 5 al. in Int J Surg
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