Postoperative Pancreatic Fistula Rates Climb Amid Racial Disparities

Despite advancements in surgical techniques, the incidence of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy has risen, increasing from 13.3% in 2018 to 15.7% in 2023. Racial disparities impact outcomes, with Asian and other non-White patients facing higher risks. Conversely, preoperative chemotherapy appears to reduce POPF likelihood. This analysis, based on a large cohort of 28,100 patients, underscores a persistent challenge in postoperative care.