Examining outcomes in metastatic colorectal cancer treatment, researchers conducted a review, analyzing six selected studies. Comparing surgical interventions on the liver and peritoneum, cytoreductive surgery with heated intraperitoneal chemotherapy showed comparable safety and survival outcomes to hepatectomy. This suggests a need for early integration of cytoreduction in the management algorithm for colorectal cancer patients with peritoneal metastases. The study encourages a shift in approach for improved perioperative and oncological outcomes in this patient population.
Review by Cos H and Shen P in J Surg Oncol
© 2023 The Authors. Journal of Surgical Oncology published by Wiley Periodicals LLC.