Innovative EUS Techniques Transform Access for Biliary Interventions in Complex Anatomy

New endoscopic methods, EDGE and EDEE, revolutionize access to the biliary system for patients with surgically altered anatomy. These techniques facilitate minimally invasive procedures, significantly lowering morbidity rates while maintaining high success rates. By using lumen-apposing metal stents, they improve safety profiles and expand treatment options. This comprehensive review underscores the need for multicenter trials to standardize these promising interventions in clinical practice, paving the way for future advancements in therapeutic endoscopy.