Optimizing Surgical Approach in Synchronous Colorectal Liver Metastases

Analyzing data from 976 patients with synchronous colorectal liver metastases, researchers compared simultaneous and staged resections. Simultaneous resection, beneficial for low to moderate tumor burden and node-negative right-sided primary tumors, showed increased complications in high tumor burden cases. Staged resection demonstrated better outcomes for patients with node-positive left-sided primaries and higher tumor burden scores. Tailoring the approach based on preoperative tumor burden enhances postoperative outcomes in synchronous colorectal liver metastases.