Minimally invasive radical cholecystectomy provides promising long-term survival for gallbladder cancer patients.

• 222 suspected gallbladder cancer patients underwent minimally invasive surgery, revealing a median overall survival of 60 months.
• Early-stage (T1/T2) patients had a significantly higher median survival of 66 months versus 36 months for locally advanced (T3/T4) cases.

Surgeons should consider this technique in appropriate candidates, as it shows no port-site recurrences and favorable survival based on nodal status.

• Node-negative patients had a median survival of 68 months compared to 34 months for node-positive.