Long-term Survival Outcomes of Liver Resection for Metastatic Anal Squamous Cell Carcinoma

The study evaluated the outcomes of liver resection in patients with metastatic anal squamous cell carcinoma (SCC) to the liver. Among the 21 patients undergoing liver resection and/or ablation, 95% had undergone the Nigro protocol for the primary tumor, with 57% experiencing a complete response. The median overall survival was 32.2 months, and the 5-year overall survival rate was 50%. The most common site of recurrence was the liver. Liver resection can be a beneficial treatment option for carefully selected patients with metastatic anal SCC.