Timing of EUS-Guided Drainage for Postoperative Pancreatic Fluid Collections

Early endoscopic ultrasound (EUS)-guided drainage can effectively manage postoperative pancreatic fluid collections (POPFCs) without increasing adverse events. Six retrospective studies involving 128 and 107 patients were analyzed, with the threshold for early and delayed drainage ranging from 14 to 30 days. Distal pancreatectomy was the main cause of POPFCs. The pooled odds ratio for adverse events was 0.81, indicating no significant difference between early and delayed drainage. There were no procedure-related mortalities, and technical success was achieved in all cases.