Elevated preoperative C-reactive protein levels can predict the complexity of laparoscopic appendectomy, aiding in better patient selection.

• A CRP cut-off of 220 mg/l indicates an 87% sensitivity and 90% specificity for predicting conversion to open surgery.
• The area under the ROC curve is 0.941, demonstrating strong diagnostic accuracy.

This information can guide surgeons in deciding on surgical approaches and managing postoperative care more effectively.

• Positive predictive value is 87%, with a negative predictive value of 93%.