A preoperative weight loss program significantly improves outcomes for colorectal cancer patients with excess weight.

• 61% of patients in the diet intervention lost 5% or more of their weight, compared to just 9% in usual care (odds ratio 16.8).
• Average weight loss in the intervention group was 6.1 kg, 4.3 kg more than controls.

Patient retention was 100%, with no safety concerns reported.

• Weight loss correlates with improved postoperative outcomes: losing 3.2% or more cuts complications by 50%.