Contrast-enhanced computed tomography can predict metastatic potential of small nonfunctioning pancreatic neuroendocrine tumors.

Tumor vascularity on contrast-enhanced computed tomography was studied for its predictive value in determining metastatic potential in small nonfunctioning pancreatic neuroendocrine tumors. The study included 77 patients who underwent pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors, with a focus on small tumors (≤2.0 cm). The results showed that the computed tomography a/e ratio was a useful predictor of the metastatic potential of these tumors, specifically in relation to the degree of fibrosis and the presence of microscopic venous invasion. These findings can potentially guide decision-making regarding the observation of small tumors.