Higher cholesterol and HbA1c levels increase the risk of recurrent bile duct stones after ERCP.

• Cholesterol and HbA1c >6.5% are key risk factors for recurrence.
• Triglycerides and HDL levels are protective against stone formation.

Consider lipid management and medications like statins and aspirin in patient care to potentially lower recurrence rates.

• Study involved 5,132 patients; outcomes vary across different metabolic subgroups.