Combining sequential hepatic vein embolization with portal vein embolization significantly boosts liver volume and function before major hepatectomy.

• Future remnant liver volume regeneration improved to 35.5% with sequential embolization, versus 26.2% with portal vein embolization alone.
• Both procedures had no severe complications, indicating safety in surgical applications.

Surgeons should consider sequential embolization to optimize outcomes for patients requiring right-sided hepatectomy.

• The study included 32 patients, with eight receiving the sequential approach.