A study identifies critical thresholds for future liver remnant volume (FLRV) to reduce post-hepatectomy liver failure in cancer patients.

• FLRV of ≥30% in normal livers and ≥50% in impaired livers reduces the risk of severe morbidity.
• For every 10% increase in FLRV, the odds of severe liver failure-related complications decrease by nearly 40%.

Focus on maintaining these thresholds in surgical planning to improve patient outcomes.

• 51% overall morbidity was noted, with 3.2% experiencing grade 4/5 complications; half of these were unrelated to liver failure.