Salvage Treatment After Incomplete Rectal NET Resection Shows Promise

Salvage treatment may be warranted after incomplete resection of rectal neuroendocrine tumors due to significant residual disease concerns.

  • Incomplete resection rates: 73.1% for cold snare polypectomy; 29.8% for conventional EMR; 14.7% for endoscopic submucosal dissection.
  • Residual tumor rate with salvage treatment is 25% (CI: 12%–40%).

Individualized clinical decisions are crucial given the uncertainty in recurrence prevention.

  • Recurrence rates favor salvage treatment, showing a crude rate of 0.96%.

Meta-Analysis by Kim JH, Lee JW (…) Park SJ et 2 al. in World J Gastroenterol

©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.

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