A study shows Gallium-68 DOTATATE PET has high specificity but low sensitivity in identifying lymph node metastases in pancreatic neuroendocrine tumors, affecting surgical decisions.
- Detected suspicious lymph nodes in 24% of cases; pathology confirmed involvement in 42%.
- Sensitivity was 46%, specificity 92%, with a positive predictive value of 81%.
Consider it for preoperative evaluations, especially for small tumors, keeping in mind its limitations.
- Higher Krenning scores and larger lymph nodes correlate with true-positive results.
Journal Article by Gudmundsdottir H, Hernandez-Delima FJ (…) Cleary SP et 7 al. in BMC Surg
Copyright © 2026 Elsevier Inc. All rights reserved.
