Anti-adhesion agents significantly reduce adhesive intestinal obstruction rates in intra-abdominal surgery, impacting surgical outcomes and costs.

• Incidence of adhesive intestinal obstruction was 12.4% in patients using anti-adhesion agents, versus 18.5% in non-users.
• Patients receiving these agents had higher quality-adjusted life years (1.992 QALYs) and lower average costs ($3,794, saving $1,330).

Consider broader use of anti-adhesion agents to enhance patient outcomes and reduce hospital expenses, especially in older patients and those without chronic conditions.