Surgical management of gastro-entero-pancreatic neuroendocrine tumors is inconsistent, highlighting the need for clearer guidelines.

• Only 4% of studies on surgery for GEP-NETs are prospective; 96.7% are retrospective.
• Most research focuses on small pancreatic NETs and liver metastases, limiting broader applicability.

Surgeons should prioritize evidence from multi-institutional studies for better patient selection and outcomes.

• Current literature primarily involves single-center analyses, diminishing evidence reliability.