Sacral Neuromodulation Shows Promise in Relieving Symptoms of Low Anterior Resection Syndrome

Sacral neuromodulation may be effective in relieving symptoms of low anterior resection syndrome after rectal cancer surgery, according to the SANLARS randomized clinical trial. The trial involved 46 patients, of whom 78% experienced a ≥50% reduction in symptoms after testing. During the crossover phase, all patients showed a reduction in symptoms, with better results when the generator was active. At 6- and 12-month follow-up, significant reductions in symptom scores and improvements in quality of life were observed.