Adding indocyanine green fluorescence imaging to intraoperative ultrasound significantly improves the detection of liver cancer lesions, a crucial advancement for surgical outcomes.

• Sensitivity increases dramatically to 99.78% compared to just 86.8% with ultrasound alone.
• The combination showed a 15.07 odds ratio over ultrasound alone, indicating a substantial advantage in lesion detection.

This technique could reduce missed lesions in complex cases, improving patient outcomes and guiding surgical decisions.

• The analysis included 11 studies with 558 patients and 894 lesions, reinforcing the robust evidence for this imaging approach.