Outpatient appendectomy for uncomplicated acute appendicitis: Safe, effective, and cost-saving

The PENDI-CSI Randomized Clinical Trial assessed the safety, efficacy, and cost-effectiveness of outpatient appendectomy for uncomplicated acute appendicitis. With 85.9% of patients discharged without admission, the study found that outpatient surgery is safe and effective. Predictors for admission included age over 31 years, hypertension, high anesthetic risk, previous abdominal surgery, postoperative pain, and fear. There were no differences in complications or readmissions between outpatient and inpatient surgery, and the perceived quality was similar. Outpatient appendectomy resulted in significant cost savings of €1,034.97 per patient.