Incidentally detected T2 gallbladder cancer associated with poorer outcomes compared to upfront surgery

Incidentally detected T2 gallbladder cancer (pt2 GBC) has been found to have significantly worse outcomes compared to similarly staged patients who undergo upfront radical cholecystectomy. A retrospective analysis of 425 cases revealed that patients with incidentally detected tumors had higher rates of locoregional, liver, and abdominal wall recurrences. The five-year disease-free survival rate was lower in the incidentally detected group. These findings highlight the importance of early detection and prompt treatment for better outcomes in pt2 GBC.