Higher Rate of Recurrence with Hybrid Resection for Laterally Spreading Lesions of the Papilla

Hybrid resection (HR) for laterally spreading lesions of the papilla, involving hot snare papillectomy and cold snare resection, was compared to conventional hot snare resection (CR) in a study. HR was associated with a significantly higher recurrence rate of recurrent or residual adenoma (RRAs) compared to CR. The odds of recurrence were 3.6 times higher with HR. HR also required a higher median number of procedures to treat RRAs. However, there was no difference between the two techniques in terms of bleeding risk. The study suggests that CR should remain the preferred management option for treating these lesions.