Researchers analysed 338 cyst fluid samples from 190 IPMN patients and found no significant difference in microbiome signatures compared to negative controls. In patients who recently had invasive procedures, a gut-associated microbe outlier signal was evident. The study concluded that IPMNs and pancreatic cystic neoplasms do not have a distinct microbiome, supporting the concept of a sterile environment, with outlier signals potentially appearing post-endoscopic procedures. No correlations were found between microbial patterns and clinical or cyst parameters.
Journal Article by Pust MM, Rocha Castellanos DM (…) Xavier RJ et 6 al. in Gut
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