En-bloc resection of well-differentiated nonampullary duodenal neuroendocrine tumors is safe and effective

Endoscopic resection of well-differentiated nonampullary duodenal neuroendocrine tumors was safe and effective, with a high rate of en-bloc and R0 resections. Tumors located in the second part of the duodenum, ≥10mm in size, and with muscularis propria invasion were risk factors for non-curative resection. Adverse events were rare and successfully managed. Long-term outcomes showed low rates of recurrence and metastasis, making this treatment favorable for patients without regional lymph node or distant metastasis.