Discrepancies in Software Algorithms for Visceral Perfusion Assessment

Quantification of fluorescence angiography for visceral perfusion assessment revealed a mean relative difference of +58.2% in normalized maximum slope measurements between two software algorithms. The agreement deteriorated at higher values, suggesting a linear bias. These discrepancies highlight potential limitations in the external validity of quantitative indocyanine green fluorescence angiography parameters, urging caution in their interpretation.