Low Intrinsic Pancreatic Microbiome Biomass Across Neoplastic Conditions

A comprehensive assessment of the intrinsic pancreatic microbiome across diverse neoplastic conditions found very low biomass, consistent microbial composition, and no differences between normal pancreas, ipmn, or pdac. Dysplastic ipmn showed low bacterial abundances with minor compositional changes in cyst fluid, indicating an unlikely role in malignant transformation.