Whole Blood Hemostatic Resuscitation in Geriatric Trauma: Impact on Mortality

A nationwide study examined the impact of whole blood (WB) hemostatic resuscitation on geriatric trauma patients with severe hemorrhagic shock. Among 1,194 patients identified, 141 (12%) received WB in addition to component therapy (CT). Multivariable analysis revealed that WB use was associated with reduced 24-hour mortality (odds ratio 0.62, 95% CI 0.41-0.94, p = 0.024) and in-hospital mortality (odds ratio 0.60, 95% CI 0.40-0.90, p = 0.013) compared to CT alone. These findings suggest WB resuscitation may improve early and overall mortality in geriatric trauma patients with hemorrhagic shock.