Antibiotics Post-Pancreaticoduodenectomy Reduce Major Complications

Postoperative antibiotic prophylaxis in pancreaticoduodenectomy bile duct stenting patients significantly reduced major complications such as reoperation and intensive care unit readmission. Targeted antibiotic treatment based on the biliary microbiome decreased the likelihood of developing wound infections. The study emphasizes the importance of appropriate antibiotic prophylaxis in reducing postoperative complications in this patient population.