Endoscopic Treatments for Gastroesophageal Reflux Disease: EBL and TIF Show Superior Efficacy

Endoscopic band ligation (EBL) and transoral incisionless fundoplication (TIF) show comparable efficacy in improving health-related quality of life in patients with GERD, outperforming other endoscopic interventions like Stretta, EFTP, and Endocinch. EBL and TIF also significantly decrease esophagitis incidence compared to PPIs. While TIF increases lower esophageal sphincter pressure, it is less effective than PPIs in reducing esophageal acid exposure. The study suggests that EBL and TIF may be superior treatments for GERD, providing valuable insights into the relative effects of different endoscopic therapies for this condition.