A randomized trial involving 89 patients undergoing elective anal fistula or hemorrhoid surgery revealed that an enhanced recovery protocol utilizing multimodal analgesia substantially decreased oral opioid consumption in the first postoperative week. Patients in the enhanced recovery group reported median oral morphine milligram equivalent (mme) use of 8 mg versus 79 mg in the standard care group (p = 0.002). No significant differences were observed in secondary outcomes, indicating safety of the multimodal approach.
• Why it matters: Reducing opioid dependence is crucial in postoperative care.
Journal Article by Yao LY, Parrish AB, Fleshner PR and Zaghiyan KN in Dis Colon Rectum
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