Stool-based surveillance reduces colonoscopies after polypectomy

Stool-based surveillance strategies may safely decrease colonoscopy demand by 15-41% following polypectomy, according to the MOCCAS study. Conducted on 3,453 individuals, the study demonstrated that multitarget stool DNA tests and fecal immunochemical tests (FIT) were effective alternatives, especially for those at lower risk. Long-term simulations indicated that while multitarget stool DNA testing incurred higher costs, FIT-based approaches proved cost-saving. These findings highlight an evolving approach to colorectal cancer surveillance with potential benefits for patients and healthcare systems.