Persistent acute kidney injury worsens outcomes in liver surgery

In a study involving 990 liver resection patients, persistent acute kidney injury (AKI) was linked to significantly worse postoperative outcomes, including increased morbidity, extended hospital stays, and higher 90-day mortality rates. Among 384 patients with hepatocellular carcinoma, persistent AKI correlated with poorer overall survival, identified as an independent poor prognostic factor. Key predictors of persistent AKI included chronic kidney disease, albumin-bilirubin grade ≥2, and anatomical resection, emphasizing the need for effective prevention strategies.