Whole blood resuscitation reduces trauma mortality rates significantly.

Whole blood (wb) resuscitation shows significant benefits in trauma patients, leading to lower odds of mortality at 4-hour, 24-hour, and 30-day intervals compared to component-only transfusions. Data from 12,275 patients indicate that higher wb to total transfusion volume (wb:ttv) ratios further decrease mortality, with each 10% increase correlating to a 13% reduction in 4-hour mortality odds. Balanced blood component transfusions alongside wb also notably enhance survival rates.