A systematic review and meta-analysis encompassing 14 studies reveal that colorectal cancer patients with peritoneal metastases experience enhanced overall survival (OS) and relapse-free survival (RFS) following cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). Compared to control regimens, the CRS + HIPEC approach markedly improves these outcomes, shedding light on effective therapeutic strategies for managing advanced disease stage in colorectal cancer.
Meta-Analysis by Peng W, Li J (…) Lu J et 3 al. in Ann Ital Chir