Endoscopic characterization outperforms biopsies in treatment planning

Effective endoscopic characterization for colorectal lesions >2 cm leads to better treatment outcomes compared to non-targeted and targeted biopsies. In a study of 84 patients, endoscopic methods proposed adequate treatment in 52.3 to 70.5% of cases, while biopsies resulted in 72.7% and 69.3% respectively. However, biopsy strategies risk under-treatment in nearly a third of cases, while endoscopic characterization maintains a low 5% under-treatment risk. More focused criteria are needed for optimal lesion characterization.