Indocyanine Green Fluorescence Angiography Reduces Colorectal Surgery Leak Rates

Indocyanine green fluorescence angiography (ICGFA) significantly lowers anastomotic leak rates during colorectal surgery. Analysis of 45 studies involving 14,333 patients revealed overall leak rates of 4.5% with ICGFA compared to 8.5% without it (OR: 0.47, p < 0.001). Notably, in rectal resections, leaks occurred at 4.7% with ICGFA versus 11.5% without (OR: 0.38, p < 0.0001). ICGFA also led to a change in surgical strategy in 8.4% of cases, reinforcing its clinical utility.