ctDNA monitoring may extend surveillance intervals in colorectal cancer

Findings indicate that integrating digital PCR-based ctDNA monitoring into postoperative colorectal cancer surveillance could significantly extend CT scan intervals. Analysis of 52 patients showed that traditional monitoring led to potential delays in clinical relapse detection. In contrast, ctDNA monitoring provided a median lead time of 339 days, suggesting that 57.1% of conventional CT scans could be avoided without compromising patient safety. These results emphasize a shift towards more efficient surveillance methods in managing colorectal cancer.