Broad implementation of Watch-and-Wait for rectal cancer in the Netherlands shows promising results. Among 1,080 patients, 45% achieved clinical complete response post-treatment, with a three-year organ preservation rate of 76%. The study also found a 23% incidence of local regrowth and an overall survival rate of 97%. Notably, no significant differences in regrowth or metastases arose between the study’s cohorts, indicating successful application of treatment protocols in high-volume hospitals.
Multicenter Study by Geubels BM, Grotenhuis BA (…) Beets GL et 5 al. in Br J Surg
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