Lactated Ringer’s solution reduces severe pancreatitis risk

A meta-analysis of 1,500 acute pancreatitis patients demonstrated that lactated Ringer’s solution significantly lowers the risk of developing moderate-to-severe pancreatitis compared to normal saline (odds ratio 0.48). Additionally, patients receiving lactated Ringer’s experienced shorter hospital stays, reduced ICU admissions (relative risk 0.42), and fewer local complications (relative risk 0.58). Although there were no significant differences in mortality or organ failure rates, the results suggest lactated Ringer’s offers superior clinical outcomes in fluid resuscitation for acute pancreatitis.