Application of glubran 2, a cyanoacrylate-based sealant, in ileocolic anastomoses during right colectomy significantly reduced anastomotic leak (AL) rates from 6.18% to 1.85% (p<0.01). This multicenter study involved 380 patients across seven hospitals and demonstrated that the sealant also provides protective effects in patients with known risk factors, such as smoking and diabetes. The findings suggest glubran 2’s potential as a beneficial adjunct in colorectal surgery, warranting further research.
Journal Article by Rega D, Giulio E (…) Delrio P et 14 al. in Ann Coloproctol