Dynamic risk stratification improves identification of high-risk patients

A study analyzing data from 234 pancreatoduodenectomy patients established that dynamic risk stratification using serum pancreatic amylase and other biomarkers can effectively identify those at high risk for clinically relevant postoperative pancreatic fistula (POPF). The findings indicate that serum pancreatic amylase levels on postoperative days 1 and 2 are critical in risk assessment. Combining serum pancreatic amylase with drain amylase and C-reactive protein enhances diagnostic accuracy, reaching 87% in identifying at-risk patients by day three.