Lidocaine outperforming nifedipine in hemorrhoid pain relief

A retrospective cohort study of 123 acute hemorrhoidal disease patients revealed that a treatment regimen including oral diosmin/hesperidin, bromelain, and topical lidocaine resulted in faster pain relief and improved symptom scores compared to a nifedipine-based regimen. Significant differences were noted by day 7 in pain scores (0.17 vs. 2.20, p < 0.001) and the hemorrhoidal disease symptom score (0.02 vs. 10.16, p < 0.001). Both treatments were well tolerated with no adverse events reported.