New nomogram predicts survival for signet ring cell gastric cancer patients

A novel prognostic nomogram has been developed for predicting overall survival (OS) and cancer-specific survival (CSS) in signet ring cell gastric cancer patients post-surgery. Analyzing data from 3,481 patients, researchers identified critical independent prognostic factors, including race, chemotherapy, and lymph node ratio. The nomogram demonstrated impressive accuracy with a c-index of 0.748 for OS and 0.763 for CSS. Validation cohorts also showed strong predictive performance, suggesting the nomogram could significantly aid personalized treatment decisions.