Biliary stenting with 125I seeds enhances survival and stent patency.

A meta-analysis of 14 studies involving 1,078 patients indicates that biliary stenting combined with intraluminal 125I seed brachytherapy significantly improves overall survival and stent patency compared to standard biliary stenting alone. The study found no increase in complications or severe liver damage associated with the combined treatment. With longer survival and better functionality of the stent without adverse effects, clinicians may consider this approach as a safe and effective option for advanced cholangiocarcinoma patients.