Antibiotics Prove Effective in Uncomplicated Diverticulitis: A Japanese Nationwide Study

Investigating the effectiveness of antibiotics in treating uncomplicated diverticulitis, this study analyzed data from 131,936 admissions. After propensity score matching, it found that initiating antibiotics within 2 days of admission significantly reduced the rates of intestinal resection and stoma creation when compared to non-antibiotic treatment. While the antibiotic approach resulted in slightly higher median costs, it showed promise in reducing the need for surgical interventions in patients with moderate to severe disease activity. Further research is recommended to explore these findings.