Personalized Approaches to T1 Colorectal Cancer Treatment

This study explored the optimal management of T1 colorectal cancers (CRCs) in the Western hemisphere. Analyzing a significant dataset from 2004 to 2018, including 28,430 T1 CRC patients, researchers compared endoscopic therapy (ET) and surgical resection (SR) outcomes. They found that ET was safe and effective for left-sided T1N0M0 colon cancers with tumors 2 cm or smaller and T1N0M0 rectal cancers with tumors 1 cm or smaller. The study emphasizes the importance of tailored treatment based on tumor size and location to avoid over- or under-use of ET.