Liver Transplant Impact on Ileal Pouch Outcomes in PSC-IBD

For patients with primary sclerosing cholangitis and inflammatory bowel disease (PSC-IBD), this study explores the influence of liver transplantation (LT) on ileal pouch-anal anastomosis (IPAA) outcomes. Among 160 patients, LT correlated with higher chronic pouchitis rates but didn’t affect overall and pouch survival. Nontransplanted patients had more PSC-related deaths. IPAA timing regarding LT didn’t impact short- or long-term pouch outcomes. Results suggest LT’s link to increased pouchitis but emphasize its minimal impact on IPAA and overall survival in PSC-IBD patients.