Unveiling liver regeneration intricacies, this study decodes Gata3 and Ramp2’s role in hepatic-vascular revival post-surgery. These hepatocyte conductors fuel liver sinusoidal endothelial cell proliferation. Pedf and Vegfa, playing contrasting roles in endothelial migration, spice up the dance. Gata3 inhibitors emerge as potential superheroes against post-hepatectomy liver failure. Serum Pedf/Vegfa Index (SPVI) steps in as a savvy predictor. It’s a symphony of hepatocyte moves, unlocking avenues for post-surgery liver recovery and potential treatment strategies.
Journal Article by Bibo W, Hao S (…) Hongyang W et 13 al. in J Hepatol
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